Mechanosensing and Chemical Signaling in Single Osteocytes

Cover of my thesis book. If you find the topics (see papers below) interesting and wish to have a copy of the thesis, which has additional chapters than the papers, do not hesitate to contact me via the 'comments' section of this post. Currently the online version of the book is not available, but it will be accessible soon.

Contents

General Abstract		09
Chapter 1	General Introduction	15
Chapter 2	The role of osteocytes in bone mechanotransduction J Klein-Nulend, A Vatsa, RG Bacabac, SD Tan, TH Smit	23
Chapter 3	Bioimaging of intracellular NO production in single bone cells after mechanical stimulation A Vatsa, D Mizuno, TH Smit, CF Schmidt, FC MacKintosh, J Klein-Nulend	45
Chapter 4	Quantification of instantaneous nitric oxide response of bone cells to mechanical and chemical stimuli D Mizuno, A Vatsa, RG Bacabac, J Klein-Nulend, TH Smit, FC MacKintosh, CF Schmidt	63
Chapter 5	Extracellular NO signaling from a mechanically stimulated osteocyte A Vatsa, TH Smit, J Klein-Nulend	85
Chapter 6	Osteocyte morphology in fibula and calvaria – is there a role for mechanosensing? A Vatsa, RG Breuls, CM Semeins, PL Salmon, TH Smit, J Klein-Nulend	103
Chapter 7	Paxilin localisation in mechanosensing osteocytes in fibula and calvaria – is it determined by the direction of mechanical loading? A Vatsa, CM Semeins, TH Smit, J Klein-Nulend	121
Chapter 8	General Discussion	135
Algemene samenvatting		147
Acknowledgments		153
Curriculum vitae		157
Publications		159